Journal: Scientific Reports

Article Title: GBR membrane of novel poly (butylene succinate-co-glycolate) co-polyester co-polymer for periodontal application

doi: 10.1038/s41598-018-25952-1

Figure Lengend Snippet: Morphology of rabbit MSCs on PBSGL nanofibers (PBSGL0 ( a ), PBSGL10 ( b ), BSGL20 ( c ) and PBSGL40 ( d )) seeded at a cell density of 4000 cells per cm 2 after 7 days’ culture. Cells were immuno-stained with an antibody against vinculin (green), FITC–phalloidin (red), and DAPI (blue). Scale bar = 100 μm.

Article Snippet: Bone marrow-derived MSCs from the femur of a 3.5 kg, male New Zealand white rabbit at skeletal maturity were ordered from the National Cell Bank, Pasteur Institute of Iran.

Techniques: Staining

Journal: Scientific Reports

Article Title: GBR membrane of novel poly (butylene succinate-co-glycolate) co-polyester co-polymer for periodontal application

doi: 10.1038/s41598-018-25952-1

Figure Lengend Snippet: Metabolic activity (proliferation) of rabbit MSCs cultured on electrospun nanofibers submerged in basal medium at day 1, 3, 7, and 12. The secondary y axis shows the number of rabbit MSCs for colored dashed lines corresponding to each group. An asterisk denotes a statistically significant difference (P < 0.05) between the test and control group at each time point. The sample size selected was 5.

Article Snippet: Bone marrow-derived MSCs from the femur of a 3.5 kg, male New Zealand white rabbit at skeletal maturity were ordered from the National Cell Bank, Pasteur Institute of Iran.

Techniques: Activity Assay, Cell Culture, Control

Journal: Scientific Reports

Article Title: GBR membrane of novel poly (butylene succinate-co-glycolate) co-polyester co-polymer for periodontal application

doi: 10.1038/s41598-018-25952-1

Figure Lengend Snippet: Osteogenic differentiation of rabbit MSCs cultured on electrospun PBSGL n membranes at days 4, 7, 14, and 21 in the osteogenic media: DNA ( a ); ALP activity ( b ); calcium content ( c ); gene expression (Col-α1 ( d ), Runx-2 ( e ), and OCN ( f )); protein expressions of OCN and Col-α1 at day 21 relative to β actin expression ( g ); Western blotting bands for OCN (12 kDa), Col-α1 (130 kDa), and β actin (42 kDa) (h). Three different gels (with the same acquisition settings and exposure parameters) were used to visualize the relative protein expressions of OCN, Col-α1 and β actin proteins. Alizarin Red staining showing deposited calcium ions on the electrospun PBSGL0 (i-1), PBSGL10, (i-2) PBSGL20, (i-3) and PBSGL40 (i-4) nanofibers at day 21. An asterisk denotes a statistically significant difference P < 0.05) between the test and control group at each time point. A “#” sign indicates a statistically significant difference between the test and all other groups at each time point. Sample size selected was 5.

Article Snippet: Bone marrow-derived MSCs from the femur of a 3.5 kg, male New Zealand white rabbit at skeletal maturity were ordered from the National Cell Bank, Pasteur Institute of Iran.

Techniques: Cell Culture, Activity Assay, Gene Expression, Expressing, Western Blot, Staining, Control

Journal: Stem Cell Research & Therapy

Article Title: Stem cell-based therapy for fibrotic diseases: mechanisms and pathways

doi: 10.1186/s13287-024-03782-5

Figure Lengend Snippet: Summary of the clinical studies regarding the utilization of stem cells in the treatment of fibrotic disorders

Article Snippet: NCT05227846 , Human Umbilical Cord-derived Mesenchymal Stem Cells for Decompensated Cirrhosis (MSC-DLC-1) , https://clinicaltrials.gov/study/NCT05227846 , RECRUITING , Decompensated Cirrhosis , BIOLOGICAL: Human Umbilical Cord-derived Mesenchymal Stem Cells , Vcanbio Cell and Gene Engineering Corp., Ltd. , PHASE1.

Techniques: Transplantation Assay, Derivative Assay, Control, Injection, Whole Blood Assay, Infection, Saline, Comparison, Virus, Filtration, Cell Culture, Sterility, Diagnostic Assay, Solvent